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KMID : 1123920180320060418
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Korean Journal of Oriental Physiology and Pathology
2018 Volume.32 No. 6 p.418 ~ p.421
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Retrospective Observation of Liver Function Test in 147 Patients Admitted to Korean Medicine Hospital
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Lee Yu-Ri
Cho Na-Kyung
Kim Kyung-Soon
Choi Hong-Sik
Kim Seung-Mo
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Abstract
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The purpose of this study was to evaluate the changes of liver function test before and after treatment in patients admitted to Korean medicine hospital. We checked liver function test level (aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase, total bilirubin, direct bilirubin) of 147 patient who admitted in Korean medicine hospital from July 1, 2015 to June 30, 2018. The subjects were selected those who took herbal medicine continuously during the admission period and who performed liver function test on admission and before discharge. And the subjects were excluded those who had a history of liver and biliary disease at the time of admission or who took hepatoprotectants. Aspartate aminotransferase, alanine aminotransferase and alkaline phosphatase significantly decreased compared with the values of admission(p<0.05), but total bilirubin and direct bilirubin were not significantly changed(p>0.05). On admission 31 patients(21.1%) had abnormal liver function and 6 patients(4.1%) had liver injury while 19 patients(12.9%) had abnormal liver function and 6 patients(4.1%) showed liver injury before discharge. This study suggests that herbal medicine may not injure liver function.
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KEYWORD
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Herbal medicine, Liver function, Drug-induced liver injury
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